Molecular drug susceptibility testing and strain typing of tuberculosis by DNA hybridization.

In Mycobacterium tuberculosis (Mtb) the detection of single nucleotide polymorphisms (SNPs) is of high importance both for diagnostics, since drug resistance is primarily caused by the acquisition of SNPs in multiple drug targets, and for epidemiological studies in which strain typing is performed b...

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Bibliographic Details
Main Authors: Hillary N Wood, Tom Venken, Hanny Willems, An Jacobs, Ana Júlia Reis, Pedro Eduardo Almeida da Silva, Susanne Homolka, Stefan Niemann, Kyle H Rohde, Jef Hooyberghs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212064