Exposure to perfluoroalkyl substances and risk of hepatocellular carcinoma in a multiethnic cohort

Exposure to perfluoroalkyl substances and risk of hepatocellular carcinoma in a multiethnic cohort

Background & Aims: Exposure to poly- and perfluoroalkyl substances (PFAS), a class of persistent organic pollutants, is ubiquitous. Animal studies suggest that PFAS may increase risk of fatty liver and hepatocellular carcinoma (HCC) via impacts on hepatic lipid, amino acid, and glucose metab...

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Bibliographic Details
Main Authors: Jesse A. Goodrich, Douglas Walker, Xiangping Lin, Hongxu Wang, Tiffany Lim, Rob McConnell, David V. Conti, Lida Chatzi, Veronica Wendy Setiawan
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:JHEP Reports
Subjects:
Chemical exposure
exposome
perfluorinated alkyl substance
hepatocellular carcinoma
metabolome
bile acid
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555922001227

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http://www.sciencedirect.com/science/article/pii/S2589555922001227

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