Development and characterization of a packaging cell line for pseudo-infectious yellow fever virus particle generation

Development and characterization of a packaging cell line for pseudo-infectious yellow fever virus particle generation

Abstract INTRODUCTION: Pseudo-infectious yellow fever viral particles (YFV-PIVs) have been used to study vaccines and viral packaging. Here, we report the development of a packaging cell line, which expresses the YFV prM/E proteins. METHODS: HEK293 cells were transfected with YFV prM/E and C (84...

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Bibliographic Details
Main Authors: Sabrina Ribeiro de Almeida Queiroz, José Valter Joaquim Silva Júnior, Andréa Nazaré Monteiro Rangel da Silva, Amanda Gomes de Oliveira Carvalho, Jefferson José da Silva Santos, Laura Helena Vega Gonzales Gil
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT)
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Yellow fever virus
Trans-packaging
Pseudo-infectious particles
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000100066&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000100066&lng=en&tlng=en

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