Cinnamaldehyde and its combination with deferoxamine ameliorate inflammation, ferroptosis and hematoma expansion after intracerebral hemorrhage in mice

Cinnamaldehyde and its combination with deferoxamine ameliorate inflammation, ferroptosis and hematoma expansion after intracerebral hemorrhage in mice

Abstract Intracerebral hemorrhage (ICH) is a most serious type of hemorrhagic stroke with a continuously rising incidence globally, without effective cure available. The underlying mechanisms driving brain injury are complex and include inflammation, oxidative stress, glutamate excitotoxicity, membr...

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Bibliographic Details
Main Authors: Yulin Liu, Guoqiang Yang, Mengnan Liu, Yuwei Zhang, Houping Xu, Maryam Mazhar
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Neuroinflammation
Subjects:
Intracerebral hemorrhage
Brain injury
Inflammation
Oxidative stress
Lipid peroxidation
Ferroptosis
Online Access:https://doi.org/10.1186/s12974-025-03373-y

Internet

https://doi.org/10.1186/s12974-025-03373-y

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