Safflower polysaccharide ameliorates acute ulcerative colitis by regulating STAT3/NF-κB signaling pathways and repairing intestinal barrier function

Safflower polysaccharide ameliorates acute ulcerative colitis by regulating STAT3/NF-κB signaling pathways and repairing intestinal barrier function

This study is to investigate the effect of SPS on the UC model. An animal model of UC induced by DSS was developed using C57BL/6 mice. The body weight was recorded every day, and the symptoms related to UC were detected. H&E staining, AB-PAS staining and PSR staining were used to evaluate the hi...

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Bibliographic Details
Main Authors: Man Qi, Shenghui Chu, Wenxuan Wang, Xianglei Fu, Chao Jiang, Liang Zhang, MD Hasan Ali, Yating Lu, Mengwei Jia, Dilraba Ubul, Hui Tang, Jian Li, Min Liu
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Safflower polysaccharide
Ulcerative colitis
Intestinal barrier
Inflammation
Intestinal flora
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224004372

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http://www.sciencedirect.com/science/article/pii/S0753332224004372

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