Possible Mechanisms of the Neuroprotective Actions of Date Palm Fruits Aqueous Extracts against Valproic Acid-Induced Autism in Rats

Possible Mechanisms of the Neuroprotective Actions of Date Palm Fruits Aqueous Extracts against Valproic Acid-Induced Autism in Rats

The current study aimed to determine how palm date aqueous fruit extracts (AFE) affected the autistic-like behaviors brought on by valproic acid (VPA) injection, as well as any potential contributions from Sirt-1, oxidative stress, apoptosis, and autophagy. The pregnant Sprague Dawley females were t...

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Bibliographic Details
Main Authors: Abdelaziz M. Hussein, Seham Ahmed Mahmoud, Khalid Mohammed Elazab, Ahmed F. Abouelnaga, Marwa Abass, Ahmed A. H. Mosa, Mennatullah A. M. Hussein, Mohamed E. G. Elsayed
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Current Issues in Molecular Biology
Subjects:
palm date extracts
VPA
autism
Sirt-1
oxidative stress
Nrf2
Online Access:https://www.mdpi.com/1467-3045/45/2/105

Internet

https://www.mdpi.com/1467-3045/45/2/105

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