The underlying regulatory mechanisms of colorectal carcinoma by combining Vitexin and Aspirin: based on systems biology, molecular docking, molecular dynamics simulation, and in vitro study

The underlying regulatory mechanisms of colorectal carcinoma by combining Vitexin and Aspirin: based on systems biology, molecular docking, molecular dynamics simulation, and in vitro study

IntroductionColorectal cancer (CRC) is a highly prevalent digestive system malignancy. Aspirin is currently one of the most promising chemopreventive agents for CRC, and the combination of aspirin and natural compounds helps to enhance the anticancer activity of aspirin. Natural flavonoids like vite...

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Bibliographic Details
Main Authors: Dengsheng Chen, Ying Chen, Fang Huang, Xiaoling Zhang, Yulv Zhou, Luning Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Endocrinology
Subjects:
colorectal cancer
vitexin
Aspirin
network pharmacology
molecular docking
experimental verification
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1147132/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1147132/full

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