The intestinal microbial metabolite nicotinamide n-oxide prevents herpes simplex encephalitis via activating mitophagy in microglia

The intestinal microbial metabolite nicotinamide n-oxide prevents herpes simplex encephalitis via activating mitophagy in microglia

Herpes simplex encephalitis (HSE), a complication of herpes simplex virus type I (HSV-1) infection causes neurological disorder or even death in immunocompromised adults and newborns. However, the intrinsic factors controlling the HSE outcome remain unclear. Here, we show that HSE mice exhibit gut m...

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Bibliographic Details
Main Authors: Feng Li, Yiliang Wang, Xiaowei Song, Zhaoyang Wang, Jiaoyan Jia, Shurong Qing, Lianzhou Huang, Yuan Wang, Shuai Wang, Zhe Ren, Kai Zheng, Yifei Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Gut Microbes
Subjects:
HSE
gut microbiota
microglia
nicotinamide n-oxide
mitophagy
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2022.2096989

Internet

https://www.tandfonline.com/doi/10.1080/19490976.2022.2096989

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