Ketone body β-hydroxybutyrate (BHB) preserves mitochondrial bioenergetics

Abstract The ketogenic diet is an emerging therapeutic approach for refractory epilepsy, as well as certain rare and neurodegenerative disorders. The main ketone body, β-hydroxybutyrate (BHB), is the primary energy substrate endogenously produced in a ketogenic diet, however, mechanisms of its thera...

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Bibliographic Details
Main Authors: I. Llorente-Folch, H. Düssmann, O. Watters, N. M. C. Connolly, Jochen H. M. Prehn
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46776-8