Rapid Screening of Permeation of Rutin through Skin Using Alaptide Enantiomers
The investigation deals with the influence of permeation of rutin from carboxymethyl cellulose gel through full-thickness pig ear skin by (S)- and (R)-alaptide as potential excipients. Alaptide, 8-methyl-6,9-diazaspiro[4.5]decan-7,10-dione, is the original Czech compound. By means of this rapid scre...
Main Authors: | Aneta Cernikova, Radka Opatrilova, Pavel Bobal, Josef Jampilek |
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Format: | Article |
Language: | English |
Published: |
International Association of Physical Chemists (IAPC)
2015-01-01
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Series: | ADMET and DMPK |
Online Access: | http://pub.iapchem.org/ojs/index.php/admet/article/view/155 |
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