Pharmacokinetics and Anti-Diabetic Studies of Gliclazide Nanosuspension

Gliclazide (GCZ), an antidiabetic medication, has poor solubility and limited oral bioavailability due to substantial first-pass metabolism. Thus, the purpose of the current study was to optimize and formulate a GCZ nanosuspension (NS) employing the antisolvent precipitation technique. A three-facto...

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Main Authors: Sunitha Sampathi, Shubham Prajapati, Vijayabhaskarreddy Junnuthula, Sathish Dyawanapelly
格式: 文件
语言:English
出版: MDPI AG 2022-09-01
丛编:Pharmaceutics
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在线阅读:https://www.mdpi.com/1999-4923/14/9/1947