Pharmacokinetics and Anti-Diabetic Studies of Gliclazide Nanosuspension

Pharmacokinetics and Anti-Diabetic Studies of Gliclazide Nanosuspension

Gliclazide (GCZ), an antidiabetic medication, has poor solubility and limited oral bioavailability due to substantial first-pass metabolism. Thus, the purpose of the current study was to optimize and formulate a GCZ nanosuspension (NS) employing the antisolvent precipitation technique. A three-facto...

Olles dieđut

Bibliográfalaš dieđut
Váldodahkkit: Sunitha Sampathi, Shubham Prajapati, Vijayabhaskarreddy Junnuthula, Sathish Dyawanapelly
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: MDPI AG 2022-09-01
Ráidu:Pharmaceutics
Fáttát:
Box–Behnken design
solubility
antisolvent precipitation
nanosuspension
quality by design
diabetes formulation
Liŋkkat:https://www.mdpi.com/1999-4923/14/9/1947

Interneahtta

https://www.mdpi.com/1999-4923/14/9/1947

Geahča maid