Evolution of <i>RAS</i> Mutations in Cell-Free DNA of Patients with Tissue <i>RAS</i> Wild-Type Metastatic Colorectal Cancer Receiving First-Line Treatment: The PERSEIDA Study

Evolution of <i>RAS</i> Mutations in Cell-Free DNA of Patients with Tissue <i>RAS</i> Wild-Type Metastatic Colorectal Cancer Receiving First-Line Treatment: The PERSEIDA Study

The serial analysis of cell-free DNA (cfDNA) enables minimally invasive monitoring of tumor evolution, providing continuous genetic information. PERSEIDA was an observational, prospective study assessing the cfDNA <i>RAS</i> (<i>KRAS</i>/<i>NRAS</i>) mutational st...

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Bibliographic Details
Main Authors: Manuel Valladares-Ayerbes, Pilar Garcia-Alfonso, Jorge Muñoz Luengo, Paola Patricia Pimentel Caceres, Oscar Alfredo Castillo Trujillo, Rosario Vidal-Tocino, Marta Llanos, Beatriz Llorente Ayala, Maria Luisa Limon Miron, Antonieta Salud, Luis Cirera Nogueras, Rocio Garcia-Carbonero, Maria Jose Safont, Esther Falco Ferrer, Jorge Aparicio, Maria Angeles Vicente Conesa, Carmen Guillén-Ponce, Paula Garcia-Teijido, Maria Begoña Medina Magan, Isabel Busquier, Mercedes Salgado, Ariadna Lloansí Vila
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
colorectal cancer
cell-free DNA
<i>RAS</i> mutations
solid biopsy
Online Access:https://www.mdpi.com/2072-6694/14/24/6075

Internet

https://www.mdpi.com/2072-6694/14/24/6075

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