Molecular Mechanism of SAHA on Regulation of Autophagic Cell Death in Tamoxifen-Resistant MCF-7 Breast Cancer Cells

<p><b>Objective: </b>Tamoxifen is currently used for the treatment of estrogen receptor-positive breast cancer patients, but acquired resistance to tamoxifen is a critical problem in breast cancer therapy. Suberoylanilide hydroxamic acid (SAHA) is a prototype of the newly developed...

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Bibliographic Details
Main Author: Young Ju Lee, A Jin Won, Jaewon Lee, Jee H. Jung, Sungpil Yoon, Byung Mu Lee, Hyung Sik Kim
Format: Article
Language:English
Published: Ivyspring International Publisher 2012-01-01
Series:International Journal of Medical Sciences
Online Access:http://www.medsci.org/v09p0881.htm