Fluorogenic and Bioorthogonal Modification of RNA Using Photoclick Chemistry

A bromoaryltetrazole-modified uridine was synthesized as a new RNA building block for bioorthogonal, light-activated and postsynthetic modification with commercially available fluorescent dyes. It allows “photoclick”-type modifications by irradiation with light (300 nm LED) at in...

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Bibliographic Details
Main Authors: Katja Krell, Hans-Achim Wagenknecht
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/3/480