A candidate approach implicates the secreted Salmonella effector protein SpvB in P-body disassembly.

P-bodies are dynamic aggregates of RNA and proteins involved in several post-transcriptional regulation processes. P-bodies have been shown to play important roles in regulating viral infection, whereas their interplay with bacterial pathogens, specifically intracellular bacteria that extensively ma...

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Bibliographic Details
Main Authors: Ana Eulalio, Kathrin S Fröhlich, Miguel Mano, Mauro Giacca, Jörg Vogel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3046968?pdf=render