Lights, camera, path splitter: a new approach for truly simultaneous dual optical mapping of the heart with a single camera

Lights, camera, path splitter: a new approach for truly simultaneous dual optical mapping of the heart with a single camera

Abstract Background Optical mapping of transmembrane voltage and intracellular calcium is a powerful tool for investigating cardiac physiology and pathophysiology. However, simultaneous dual mapping of two fluorescent probes remains technically challenging. We introduce a novel, easy-to-use approach...

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Bibliographic Details
Main Authors: Rafael Jaimes, Damon McCullough, Bryan Siegel, Luther Swift, James Hiebert, Daniel McInerney, Nikki Gillum Posnack
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Biomedical Engineering
Subjects:
Optical mapping
Calcium cycling
Transmembrane voltage
Electrophysiology
Online Access:http://link.springer.com/article/10.1186/s42490-019-0024-x

Internet

http://link.springer.com/article/10.1186/s42490-019-0024-x

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