DNA Damage Induction Alters the Expression of Ubiquitin and SUMO Regulators in Preimplantation Stage Pig Embryos

DNA Damage Induction Alters the Expression of Ubiquitin and SUMO Regulators in Preimplantation Stage Pig Embryos

DNA damage in early-stage embryos impacts development and is a risk factor for segregation of altered genomes. DNA damage response (DDR) encompasses a sophisticated network of proteins involved in sensing, signaling, and repairing damage. DDR is regulated by reversible post-translational modificatio...

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Bibliographic Details
Main Authors: Zigomar da Silva, Werner Giehl Glanzner, Luke Currin, Mariana Priotto de Macedo, Karina Gutierrez, Vanessa Guay, Paulo Bayard Dias Gonçalves, Vilceu Bordignon
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
swine
embryo development
ubiquitylation
SUMOylation
DNA damage
Online Access:https://www.mdpi.com/1422-0067/23/17/9610

Internet

https://www.mdpi.com/1422-0067/23/17/9610

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