Dimensionality reduction and recurrence analysis reveal hidden structures of striatal pathological states

A pipeline is proposed here to describe different features to study brain microcircuits on a histological scale using multi-scale analyses, including the uniform manifold approximation and projection (UMAP) dimensional reduction technique and modularity algorithm to identify neuronal ensembles, Runs...

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Bibliographic Details
Main Authors: Miguel Serrano-Reyes, Jesús Esteban Pérez-Ortega, Brisa García-Vilchis, Antonio Laville, Aidán Ortega, Elvira Galarraga, Jose Bargas
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Systems Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnsys.2022.975989/full