Single-cell RNA sequencing reveals a landscape and targeted treatment of ferroptosis in retinal ischemia/reperfusion injury

Single-cell RNA sequencing reveals a landscape and targeted treatment of ferroptosis in retinal ischemia/reperfusion injury

Abstract Background The aim of this study was to establish a complete retinal cell atlas of ischemia–reperfusion injury by single-cell RNA sequencing, and to explore the underlying mechanism of retinal ischemia–reperfusion injury in mice. Methods Single-cell RNA sequencing was used to evaluate chang...

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Bibliographic Details
Main Authors: Yangyang Li, Yuwen Wen, Xiuxing Liu, Zhuang Li, Bingying Lin, Caibin Deng, Ziyu Yu, Yingting Zhu, Ling Zhao, Wenru Su, Yehong Zhuo
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Journal of Neuroinflammation
Subjects:
Single-cell RNA sequencing
Retinal ischemia–reperfusion injury
Ferroptosis
Fer-1
Online Access:https://doi.org/10.1186/s12974-022-02621-9

Internet

https://doi.org/10.1186/s12974-022-02621-9

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