Glanzmann Thrombasthenia in Pakistani Patients: Identification of 7 Novel Pathogenic Variants in the Fibrinogen Receptor αIIbβ3

Glanzmann Thrombasthenia in Pakistani Patients: Identification of 7 Novel Pathogenic Variants in the Fibrinogen Receptor αIIbβ3

Glanzmann thrombasthenia (GT) is a rare autosomal recessive inherited platelet disorder occurring frequently in populations with high incidence of consanguineous marriages. GT is characterized by quantitative and/or qualitative defect of the platelet αIIbβ3 (GPIIb/IIIa) receptor caused by pathogenic...

Full description

Bibliographic Details
Main Authors: Muhammad Younus Jamal Siddiqi, Doris Boeckelmann, Arshi Naz, Ayisha Imran, Shariq Ahmed, Akbar Najmuddin, Barbara Zieger
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cells
Subjects:
Glanzmann thrombasthenia
inherited platelet disorder
consanguineous
ITGA2B
ITGB3
Pakistan
Online Access:https://www.mdpi.com/2073-4409/12/2/213

Internet

https://www.mdpi.com/2073-4409/12/2/213

Similar Items