Synergistic prevention and reparative effects of sesquiterpene farnesol in a rabbit model of surgical resection-induced osteoarthritis

Articular cartilage may regenerate poorly after injury or during aging. In vitro, farnesol can modulate extracellular matrix synthesis and restore chondrocyte phenotypes by increasing type II collagen (COL II) and glycosaminoglycan (GAG) production. Here, we evaluated farnesol's preventive and...

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Bibliographic Details
Main Authors: Chun Yu Chen, Shyh Ming Kuo, Guan Xuan Wu, Shan Wei Yang
Format: Article
Language:English
Published: AIP Publishing LLC 2023-03-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0129530