Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors

Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors

Abstract The ability Gram-negative pathogens have at adapting and protecting themselves against antibiotics has increasingly become a public health threat. Data-driven models identifying molecular properties that correlate with outer membrane (OM) permeation and growth inhibition while avoiding effl...

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Bibliographic Details
Main Authors: Pedro D. Manrique, Inga V. Leus, César A. López, Jitender Mehla, Giuliano Malloci, Silvia Gervasoni, Attilio V. Vargiu, Rama K. Kinthada, Liam Herndon, Nicolas W. Hengartner, John K. Walker, Valentin V. Rybenkov, Paolo Ruggerone, Helen I. Zgurskaya, S. Gnanakaran
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-024-01161-y

Internet

https://doi.org/10.1038/s42004-024-01161-y

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