Anti-Inflammatory Effects of Endogenously Released Adenosine in Synovial Cells of Osteoarthritis and Rheumatoid Arthritis Patients

Anti-Inflammatory Effects of Endogenously Released Adenosine in Synovial Cells of Osteoarthritis and Rheumatoid Arthritis Patients

Exogenous adenosine and its metabolite inosine exert anti-inflammatory effects in synoviocytes of osteoarthritis (OA) and rheumatoid arthritis (RA) patients. We analyzed whether these cells are able to synthesize adenosine/inosine and which adenosine receptors (ARs) contribute to anti-inflammatory e...

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Bibliographic Details
Main Authors: Rebecca Sohn, Marius Junker, Andrea Meurer, Frank Zaucke, Rainer H. Straub, Zsuzsa Jenei-Lanzl
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
adenosine
inosine
rheumatoid arthritis
osteoarthritis
synoviocytes
inflammation
Online Access:https://www.mdpi.com/1422-0067/22/16/8956

Internet

https://www.mdpi.com/1422-0067/22/16/8956

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