Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling

Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling

The cytochrome P450 reductase (POR) transfers electrons to all microsomal cytochrome P450 enzymes (CYP450) thereby driving their activity. In the vascular system, the POR/CYP450 system has been linked to the production of epoxyeicosatrienoic acids (EETs) but also to the generation of reactive oxygen...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Melina Lopez, Pedro F. Malacarne, Deepak P. Ramanujam, Timothy Warwick, Niklas Müller, Jiong Hu, Matthias Dewenter, Andreas Weigert, Stefan Günther, Ralf Gilsbach, Stefan Engelhardt, Ralf P. Brandes, Flávia Rezende
स्वरूप: लेख
भाषा:English
प्रकाशित: Frontiers Media S.A. 2022-12-01
श्रृंखला:Frontiers in Physiology
विषय:
cytochrome P450 reductase
cardiac remodelling
echocardiography
endothelial cells
cardiac myocytes
transverse aortic constriction
ऑनलाइन पहुंच:https://www.frontiersin.org/articles/10.3389/fphys.2022.1056369/full

इंटरनेट

https://www.frontiersin.org/articles/10.3389/fphys.2022.1056369/full

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