Clinical Significance of the Expression of Co-Stimulatory Molecule B7-H3 in Papillary Thyroid Carcinoma

Background: B7-H3, also known as CD276, an important immune checkpoint member of the B7-CD28 family, is confirmed as a promising target after PD-L1 in clinical trials. Although the overexpression of B7-H3 has been associated with invasive metastatic potential and poor prognosis in multiple types of...

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Bibliographic Details
Main Authors: Bohui Zhao, Zehao Huang, Xinyi Zhu, Huizhu Cai, Yingcheng Huang, Xiwei Zhang, Zongmin Zhang, Haizhen Lu, Changming An, Lijuan Niu, Zhengjiang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.819236/full