Roles of tumor necrosis factor-like ligand 1A in γδT-cell activation and psoriasis pathogenesis

Roles of tumor necrosis factor-like ligand 1A in γδT-cell activation and psoriasis pathogenesis

BackgroundInterleukin (IL)-17-producing γδT (γδT17) cells mediate inflammatory responses in barrier tissues. Dysregulated γδT17 cell activation can lead to the overproduction of IL-17 and IL-22 and the development of inflammatory diseases, including psoriasis. IL-23 and IL-1β are known to synergisti...

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Bibliographic Details
Main Authors: Shangyi Wang, Mina Kozai, Masaya Hiraishi, Md. Zahir Uddin Rubel, Osamu Ichii, Mutsumi Inaba, Kazuhiro Matsuo, Kensuke Takada
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
γδ T cells
psoriasis
cytokine
IL-22
IL-17
TL1A
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1340467/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1340467/full

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