Melatonin as an immunomodulator in CD19-targeting CAR-T cell therapy: managing cytokine release syndrome
Abstract Background Chimeric antigen receptor CAR-T cell therapies have ushered in a new era of treatment for specific blood cancers, offering unparalleled efficacy in cases of treatment resistance or relapse. However, the emergence of cytokine release syndrome (CRS) as a side effect poses a challen...
Main Authors: | , , , , , , , , |
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格式: | Article |
語言: | English |
出版: |
BMC
2024-01-01
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叢編: | Journal of Translational Medicine |
主題: | |
在線閱讀: | https://doi.org/10.1186/s12967-023-04779-z |