Generation of populations of antigen-specific cytotoxic T cells using DCs transfected with DNA construct encoding HER2/neu tumor antigen epitopes

Generation of populations of antigen-specific cytotoxic T cells using DCs transfected with DNA construct encoding HER2/neu tumor antigen epitopes

Abstract Background Recent fundamental and clinical studies have confirmed the effectiveness of utilizing the potential of the immune system to remove tumor cells disseminated in a patient’s body. Cytotoxic T lymphocytes (CTLs) are considered the main effectors in cell-mediated antitumor immunity. A...

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Bibliographic Details
Main Authors: Maria Kuznetsova, Julia Lopatnikova, Julia Khantakova, Rinat Maksyutov, Amir Maksyutov, Sergey Sennikov
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Immunology
Subjects:
Cytotoxic T cells
CTLs
Antigen-specific cells
Dendritic cells
HER2/neu
Tumor-associated antigen
Online Access:http://link.springer.com/article/10.1186/s12865-017-0219-7

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http://link.springer.com/article/10.1186/s12865-017-0219-7

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