The Function of the Hypothalamic–Pituitary–Adrenal Axis During Experimental Autoimmune Encephalomyelitis: Involvement of Oxidative Stress Mediators

Multiple sclerosis (MS) is an inflammatory, demyelinating disease with an unknown origin. Previous studies showed the involvement of the hypothalamic–pituitary–adrenal (HPA) axis to susceptibility to autoimmune diseases, including MS, and its best-characterized animal model, experimental autoimmune...

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Main Authors: Svetlana Trifunovic, Ivana Stevanovic, Ana Milosevic, Natasa Ristic, Marija Janjic, Ivana Bjelobaba, Danijela Savic, Iva Bozic, Marija Jakovljevic, Katarina Tesovic, Danijela Laketa, Irena Lavrnja
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.649485/full