Insulin-like growth factor-1 stimulates retinal cell proliferation via activation of multiple signaling pathways

Insulin-like growth factor-1 stimulates retinal cell proliferation via activation of multiple signaling pathways

Insulin-like growth factor-1 (IGF-1) plays critical roles in the development of the central nervous system (CNS), including the retina, regulating cell proliferation, differentiation, and survival. Here, we investigated the role of IGF-1 on retinal cell proliferation using primary cultures from rat...

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Bibliographic Details
Main Authors: Camila Saggioro de Figueiredo, Ícaro Raony, Simone Vidal Medina, Eliezer de Mello Silva, Aline Araujo dos Santos, Elizabeth Giestal-de-Araujo
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Neurobiology
Subjects:
Cell proliferation
Central nervous system
Epidermal growth factor
Insulin-like growth factor-1
Retina
Signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2665945X22000419

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http://www.sciencedirect.com/science/article/pii/S2665945X22000419

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