Pathway2Targets: an open-source pathway-based approach to repurpose therapeutic drugs and prioritize human targets

Background Recent efforts to repurpose existing drugs to different indications have been accompanied by a number of computational methods, which incorporate protein-protein interaction networks and signaling pathways, to aid with prioritizing existing targets and/or drugs. However, many of these exi...

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Bibliographic Details
Main Authors: Mauri Dobbs Spendlove, Trenton M. Gibson, Shaney McCain, Benjamin C. Stone, Tristan Gill, Brett E. Pickett
Format: Article
Language:English
Published: PeerJ Inc. 2023-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/16088.pdf