Protective Role of trans-Chalcone against the Progression from Simple Steatosis to Non-alcoholic Steatohepatitis: Regulation of miR-122, 21, 34a, and 451

Protective Role of trans-Chalcone against the Progression from Simple Steatosis to Non-alcoholic Steatohepatitis: Regulation of miR-122, 21, 34a, and 451

Purpose: Non-alcoholic steatohepatitis (NASH) is an inflammatory disorder and an aggressive form of fatty liver disease. Certain microRNAs, including miR-122, 21, 34a, and 451, are involved in the transition from steatosis to NASH. This study examined how trans-chalcone (the core of chalcone derivat...

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Bibliographic Details
Main Authors: Elham Karimi-Sales, Sajad Jeddi, Abbas Ebrahimi-Kalan, Mohammad Reza Alipour
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2022-01-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
non-alcoholic steatohepatitis
trans-chalcone
mirnas
liver
rat
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-12-200.pdf

Internet

https://apb.tbzmed.ac.ir/PDF/apb-12-200.pdf

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