Role of A-Kinase Anchoring Protein 1 in Retinal Ganglion Cells: Neurodegeneration and Neuroprotection

Role of A-Kinase Anchoring Protein 1 in Retinal Ganglion Cells: Neurodegeneration and Neuroprotection

A-Kinase anchoring protein 1 (AKAP1) is a multifunctional mitochondrial scaffold protein that regulates mitochondrial dynamics, bioenergetics, and calcium homeostasis by anchoring several proteins, including protein kinase A, to the outer mitochondrial membrane. Glaucoma is a complex, multifactorial...

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Bibliographic Details
Main Authors: Tonking Bastola, Guy A. Perkins, Keun-Young Kim, Seunghwan Choi, Jin-Woo Kwon, Ziyao Shen, Stefan Strack, Won-Kyu Ju
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cells
Subjects:
AKAP1
DRP1
mitochondrial dynamics
mitochondrial fission
glaucoma
retinal ganglion cell
Online Access:https://www.mdpi.com/2073-4409/12/11/1539

Internet

https://www.mdpi.com/2073-4409/12/11/1539

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