The Contribution of the Minimal Promoter Element to the Activity of Synthetic Promoters Mediating CAR Expression in the Tumor Microenvironment

The Contribution of the Minimal Promoter Element to the Activity of Synthetic Promoters Mediating CAR Expression in the Tumor Microenvironment

Harnessing immune effector cells to benefit cancer patients is becoming more and more prevalent in recent years. However, the increasing number of different therapeutic approaches, such as chimeric antigen receptors and armored chimeric antigen receptors, requires constant adjustments of the transge...

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Bibliographic Details
Main Authors: Yariv Greenshpan, Omri Sharabi, Ksenia M. Yegodayev, Ofra Novoplansky, Moshe Elkabets, Roi Gazit, Angel Porgador
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
CARTIV
synthetic promoter
minimal promoter
chimeric antigen receptor
Online Access:https://www.mdpi.com/1422-0067/23/13/7431

Internet

https://www.mdpi.com/1422-0067/23/13/7431

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