Molecular evolution of UCP1 and the evolutionary history of mammalian non-shivering thermogenesis

<p>Abstract</p> <p>Background</p> <p>Uncoupling protein 1 (UCP1) is a mitochondrial anion carrier, expressed in brown adipose tissue (BAT) of Eutherians. UCP1 is responsible for uncoupling mitochondrial proton transport from the production of ATP, thereby dissipating he...

Full description

Bibliographic Details
Main Authors: Klingenspor Martin, Stoneking Mark, Jastroch Martin, Hughes David A
Format: Article
Language:English
Published: BMC 2009-01-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/9/4