Loss of RNA-dependent RNA polymerase 2 (RDR2) function causes widespread and unexpected changes in the expression of transposons, genes, and 24-nt small RNAs.

Loss of RNA-dependent RNA polymerase 2 (RDR2) function causes widespread and unexpected changes in the expression of transposons, genes, and 24-nt small RNAs.

Transposable elements (TEs) comprise a substantial portion of many eukaryotic genomes and are typically transcriptionally silenced. RNA-dependent RNA polymerase 2 (RDR2) is a component of the RNA-directed DNA methylation (RdDM) silencing pathway. In maize, loss of mediator of paramutation1 (mop1) en...

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Bibliographic Details
Main Authors: Yi Jia, Damon R Lisch, Kazuhiro Ohtsu, Michael J Scanlon, Daniel Nettleton, Patrick S Schnable
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2774947?pdf=render

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http://europepmc.org/articles/PMC2774947?pdf=render

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