Evaluation of Hold-Up Volume Determination Methods and Markers in Hydrophilic Interaction Liquid Chromatography

Evaluation of Hold-Up Volume Determination Methods and Markers in Hydrophilic Interaction Liquid Chromatography

Common methods for hold-up time and volume determination in Reversed-Phase Liquid Chromatography (RPLC) have been tested for Hydrophilic Interaction Liquid Chromatography (HILIC). A zwitterionic ZIC-HILIC column has been used for the testing. The pycnometric determination method, based on difference...

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Bibliographic Details
Main Authors: Lídia Redón, Xavier Subirats, Martí Rosés
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Molecules
Subjects:
HILIC
homologous series
hold-up volume
hold-up time
retention volume
Online Access:https://www.mdpi.com/1420-3049/28/3/1372

Internet

https://www.mdpi.com/1420-3049/28/3/1372

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