Liquisolid pellets: A pharmaceutical technology strategy to improve the dissolution rate of ritonavir

Liquisolid pellets: A pharmaceutical technology strategy to improve the dissolution rate of ritonavir

Liquisolid pellets (LPs) prepared by extrusion-spheronization are promising delivery systems to improve the dissolution rate of poorly water-soluble drugs. However, developing LPs for high dose drugs (e.g. antiretroviral ritonavir, RTV) is a major challenge due to technical and quality constraints....

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Bibliographic Details
Main Authors: Brenda De Espíndola, André O'Reilly Beringhs, Diva Sonaglio, Hellen Karine Stulzer, Marcos Antônio Segatto Silva, Humberto Gomes Ferraz, Bianca Ramos Pezzini
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016419300490

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http://www.sciencedirect.com/science/article/pii/S1319016419300490

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