Enhanced differentiation of isomeric RNA modifications by reducing the size of ions in ion mobility mass spectrometric measurements
Abstract With the ability to differentiate different molecular sizes, ion mobility spectrometry (IMS) has great potentials in the analysis of isomeric compounds. However, due to the lack of sensitivity and resolution, IMS has not been commonly used. To address the issue on resolution, the goals of t...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2020-10-01
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Series: | Journal of Analytical Science and Technology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40543-020-00243-5 |