Semaphorin 7A impairs barrier function in cultured human corneal epithelial cells in a manner dependent on nuclear factor-kappa B

Semaphorin 7A impairs barrier function in cultured human corneal epithelial cells in a manner dependent on nuclear factor-kappa B

AIM: To evaluate the role of semaphorin 7A (Sema7A) and its associated regulatory mechanisms in modulating the barrier function of cultured human corneal epithelial cells (HCEs). METHODS: Barrier models of HCEs were treated with recombinant human Sema7A at concentrations of 0, 125, 250, or 500 ng/mL...

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Bibliographic Details
Main Authors: Cheng-Cheng Yang, Xiu-Xia Yang, Xiao-Jing Zhao, Heng Wang, Zi-Han Guo, Kai Jin, Yang Liu, Bin-Hui Li
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2024-03-01
Series:International Journal of Ophthalmology
Subjects:
human corneal epithelial
barrier function
transepithelial electrical resistance
zonula occludens-1
occludin
nuclear factor-kappa b
Online Access:http://ies.ijo.cn/en_publish/2024/3/20240305.pdf

Internet

http://ies.ijo.cn/en_publish/2024/3/20240305.pdf

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