Crosstalk between protein kinases AKT and ERK1/2 in human lung tumor-derived cell models

Crosstalk between protein kinases AKT and ERK1/2 in human lung tumor-derived cell models

There is no doubt that cell signaling manipulation is a key strategy for anticancer therapy. Furthermore, cell state determines drug response. Thus, establishing the relationship between cell state and therapeutic sensitivity is essential for the development of cancer therapies. In the era of person...

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Bibliographic Details
Main Authors: Aurimas Stulpinas, Matas Sereika, Aida Vitkeviciene, Ausra Imbrasaite, Natalija Krestnikova, Audrone V. Kalvelyte
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
cancer cell
cell signaling
ERK (extracellular signal-regulated kinase)
AKT
kinase inhibitors
targeted drugs
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1045521/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1045521/full

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