New sensitive method for HEPES quantification in 68Ga-radiopharmaceuticals

New sensitive method for HEPES quantification in 68Ga-radiopharmaceuticals

Abstract Background The introduction of a GMP-certified 68Ga-generator spurred the application of 68Ga-radiopharmaceuticals. Several radiosynthesis of 68Ga-radiopharmaceuticals are more efficient and robust when performed with 2-[4-(2-hydroxyethyl)piperazin-1-yl] ethanesulfonic acid (HEPES) buffer,...

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Bibliographic Details
Main Authors: I. F. Antunes, G. M. Franssen, R. Zijlma, P. Laverman, H. H. Boersma, P. H. Elsinga
Format: Article
Language:English
Published: SpringerOpen 2020-05-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
68Ga-radiopharmaceuticals
HEPES
HPLC and quality control
Online Access:http://link.springer.com/article/10.1186/s41181-020-00093-x

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http://link.springer.com/article/10.1186/s41181-020-00093-x

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