An A<sub>2A </sub>adenosine receptor agonist, ATL313, reduces inflammation and improves survival in murine sepsis models

<p>Abstract</p> <p>Background</p> <p>The pathophysiology of sepsis is due in part to early systemic inflammation. Here we describe molecular and cellular responses, as well as survival, in A<sub>2A </sub>adenosine receptor (AR) agonist treated and untreated...

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Bibliographic Details
Main Authors: Linden Joel, Obrig Tom, Lee Grace H, Martin Edward N, Moore Christopher C, Scheld W Michael
Format: Article
Language:English
Published: BMC 2008-10-01
Series:BMC Infectious Diseases
Online Access:http://www.biomedcentral.com/1471-2334/8/141