Cell Type-Specific Roles of STAT3 Signaling in the Pathogenesis and Progression of K-ras Mutant Lung Adenocarcinoma

Cell Type-Specific Roles of STAT3 Signaling in the Pathogenesis and Progression of K-ras Mutant Lung Adenocarcinoma

Worldwide, lung cancer, particularly K-ras mutant lung adenocarcinoma (KM-LUAD), is the leading cause of cancer mortality because of its high incidence and low cure rate. To treat and prevent KM-LUAD, there is an urgent unmet need for alternative strategies targeting downstream effectors of K-ras an...

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Bibliographic Details
Main Authors: Michael J. Clowers, Seyed Javad Moghaddam
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
STAT3
lung adenocarcinoma
TME
K-ras
tumor-promoting inflammation
mucosal immunology
Online Access:https://www.mdpi.com/2072-6694/14/7/1785

Internet

https://www.mdpi.com/2072-6694/14/7/1785

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