Functional Characterization of Mechanosensitive Piezo1 Channels in Trigeminal and Somatic Nerves in a Neuron-on-Chip Model

Functional Characterization of Mechanosensitive Piezo1 Channels in Trigeminal and Somatic Nerves in a Neuron-on-Chip Model

Mechanosensitive ion channels, Piezo1 and 2, are activated by pressure and involved in diverse physiological functions, including senses of touch and pain, proprioception and many more. Understanding their function is important for elucidating the mechanosensitive mechanisms of a range of human dise...

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Bibliographic Details
Main Authors: Nikita Mikhailov, Lidiia Plotnikova, Prateek Singh, Rashid Giniatullin, Riikka H. Hämäläinen
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
migraine
trigeminal
dorsal root
mechanosensitive receptors
Piezo1
calcium imaging
Online Access:https://www.mdpi.com/1422-0067/23/3/1370

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https://www.mdpi.com/1422-0067/23/3/1370

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