Formulation and Characterization of Metformin-Loaded Ethosomes for Topical Application to Experimentally Induced Skin Cancer in Mice

Formulation and Characterization of Metformin-Loaded Ethosomes for Topical Application to Experimentally Induced Skin Cancer in Mice

To achieve the best treatment of skin cancer, drug penetration inside the deepest layers of the skin is an important scientific interest. We designed an ethosome formulation that serves as a carrier for metformin and measured the in vitro skin permeation. We also aimed to measure the antitumor activ...

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Bibliographic Details
Main Authors: Ibrahim A. Mousa, Taha M. Hammady, Shadeed Gad, Sawsan A. Zaitone, Mohamed El-Sherbiny, Ossama M. Sayed
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceuticals
Subjects:
experimental skin cancer
entrapment efficacy
ethosomes
metformin
in vitro permeation
zeta potential
Online Access:https://www.mdpi.com/1424-8247/15/6/657

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https://www.mdpi.com/1424-8247/15/6/657

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