Cardioprotection by kappa-opioid receptor agonist U50488H is mediated by opioidergic regulation but not by calcium current modulation
BackgroundBecause the κ-opioid receptor (OR) agonist U50488H stimulates opioidergic regulation and inhibits L-type Ca2+ channels, this study was aimed at assessing the roles of OR and L-type Ca2+ channels on U50488H-induced cardioprotection.MethodsLangendorff-perfused rat hearts were subjected to 30...
Hauptverfasser: | , , , , |
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Format: | Artikel |
Sprache: | English |
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Korean Society of Anesthesiologists
2010-02-01
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Schriftenreihe: | Korean Journal of Anesthesiology |
Schlagworte: | |
Online Zugang: | http://ekja.org/upload/pdf/kjae-58-162.pdf |