Histone deacetylase III interactions with BK polyomavirus large tumor antigen may affect protein stability

Histone deacetylase III interactions with BK polyomavirus large tumor antigen may affect protein stability

Abstract Background Human polyomavirus BK (BKPyV) causes associated nephropathy and contributes to urinary tract cancer development in renal transplant recipients. Large tumor antigen (LT) is an early protein essential in the polyomavirus life cycle. Protein acetylation plays a critical role in regu...

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Bibliographic Details
Main Authors: Yueh-Han Hsu, Chun-Nun Chao, Hsin-Yi Huang, Pei-Wen Zhao, Pang-Hung Hsu, Cheng-Huang Shen, San-Yuan Chen, Chiung-Yao Fang
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Virology Journal
Subjects:
BKPyV
Large T antigen
Acetylation
Protein stability
HDAC3
Online Access:https://doi.org/10.1186/s12985-023-02128-6

Internet

https://doi.org/10.1186/s12985-023-02128-6

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