The conformation of the histone H3 tail inhibits association of the BPTF PHD finger with the nucleosome

The conformation of the histone H3 tail inhibits association of the BPTF PHD finger with the nucleosome

Histone tails harbor a plethora of post-translational modifications that direct the function of chromatin regulators, which recognize them through effector domains. Effector domain/histone interactions have been broadly studied, but largely using peptide fragments of histone tails. Here, we extend t...

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Bibliographic Details
Main Authors: Emma A Morrison, Samuel Bowerman, Kelli L Sylvers, Jeff Wereszczynski, Catherine A Musselman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-04-01
Series:eLife
Subjects:
nucleosome
histone tail
PHD Finger
methylation
NMR Spectroscopy
MD Simulation
Online Access:https://elifesciences.org/articles/31481

Internet

https://elifesciences.org/articles/31481

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